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Benefits of Green Tea...Cancer Related

Benefits of Green Tea...Cancer Related

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  #1  
Old 01-23-2006, 11:26 PM
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Benefits of Green Tea...Cancer Related

Benefits from Green Tea


Cancer
  • Breast cancer A recent Japanese study explored in greater detail the epidemiological findings on green tea's protection against breast cancer. In this case, women with stage I, II and III breast cancer were assessed in terms of their green tea consumption. It was found that "premenopausal women who consumed more green tea had a lower number of lymph node metastases. In postmenopausal women greater consumption of green tea correlated with increased expression of the estrogen and progesterone receptor, which implies more differentiated tumor cells and better prognosis." Finally, in a seven-year follow it was found that "women with stage I or II cancer who consumed five or more cups of green tea a day had approximately half the recurrence rate of those women who consumed four cups or less." Researchers at the Department of Surgery, Division of Oncology and. Center for Human Nutrition, University of California found that Inhibition of VEGF transcription appeared to be one of the molecular mechanism(s) involved in the antiangiogenic effects of green tea, which may contribute to its potential use for breast cancer treatment and/or prevention.
  • Colorectal cancer Department of Medicine, Case Western Reserve University reserachers found that green tea constituent epigallocatechin-3-gallate inhibits topoisomerase I activity in human colon carcinoma cells. DNA topoisomerases I and II are essential for cell survival and play critical roles in DNA metabolism and structure. Inhibitors of topoisomerase constitute a novel family of antitumor agents with demonstrated clinical activity in human malignancies. The clinical use of these agents is limited due to severe toxic effects on normal cells. Therefore, there is a need to develop novel, nontoxic topoisomerase inhibitors that have the ability to spare normal cells. Recent studies have shown that green tea and its major polyphenolic constituent, epigallocatechin-3-gallate (EGCG), impart growth inhibitory responses to cancer cells but not to normal cells. Based on the knowledge that EGCG induces DNA damage, cell cycle arrest, and apoptosis, the reserachers considered the possibility of the involvement of topoisomerase in the antiproliferative response of EGCG. Here, for the first time, we show that EGCG inhibits topoisomerase I, but not topoisomerase II in several human colon carcinoma cell lines. Based on this study it is tempting to suggest that combination of EGCG with other conventional topoisomerase inhibitors could be an improved strategy for treatment of colon cancer. They concluded the role of EGCG as a chemotherapeutic agent needed to be investigated. The Laboratory for Cancer Research at the College of Pharmacy of, Rutgers University studied the effects of green and black tea polyphenols on normal human colon mucosa and colon cancers were investigated. The results indicated that tea polyphenols can affect arachidonic acid metabolism in human colon mucosa and colon tumors, and this action may alter the risk for colon cancer in humans.
  • Esophageal cancer A study done by the College of Pharmacy, Rutgers, The State University of New Jersey, suggest that EGCG was converted to EGC in the oral cavity, and both catechins were absorbed through the oral mucosa through drinking green tea rather than using extracts. Because of the possible application of tea in the prevention of oral and esophageal cancers, the salivary levels of tea catechins were determined in six human volunteers after drinking tea. Saliva samples were collected after thoroughly rinsing the mouth with water. After drinking green tea preparations equivalent to two to three cups of tea, peak saliva levels of (-)-epigallocatechin (EGC; 11.7-43.9 microg/ml), EGC-3-gallate (EGCG; 4.8-22 microg/ml), and (-)-epicatechin (EC; 1.8-7.5 microg/ml) were observed after a few minutes. These levels were 2 orders of magnitude higher than those in the plasma. Taking tea solids in capsules resulted in no detectable salivary catechin level. Holding an EGCG solution in the mouth resulted in EGCG and EGC in the saliva and, subsequently, EGC in the urine. The present results suggest that slowly drinking tea is a very effective way of delivering rather high concentrations of catechins to the oral cavity and then the esophagus.
  • Leukemia another study found that green tea extract is a potent nucleoside transport inhibitor, interfering with tumor cells' repair of DNA after chemotherapy. Thus green tea extract "markedly potentiated" the effectiveness of chemotherapy. These findings suggest that epigallocatechin gallate and green tea extract could be used as a nontoxic adjuvant therapy for leukemia. It would also be interesting to examine how green tea polyphenols synergize with such established anti-leukemic alternative treatments as retinoic acid, Vitamin D3, DMSO, curcumin and esculetin.
  • Liver cancer A more recent study, done at the Fels Institute for Cancer Research at Temple University in Philadelphia, found that the addition of .5% of instant green tea powder to the diet of rats changed the metabolism of aflatoxin toward the formation of non-toxic hydroxylated metabolites, and decreased the binding of aflatoxin to liver-cell DNA, significantly decreasing the resulting number of pre-cancerous cells. The authors conclude that green tea protects against aflatoxin-induced liver cancer. Green tea also inhibited liver damage caused by exposure to 2-nitropropane. Even more important, green tea also protected against liver injury caused by galactosamine, which happens to be an animal model of viral hepatitis.
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Old 01-23-2006, 11:27 PM
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  • Lung cancer In a study done at the Karolinska Institute in Stockholm a team of researchers headed by Dr. Yihai Cao found that green tea can block angiogenesis-the development of new blood vessels that tumors need in order to grow and metastasize. The authors gave mice the equivalent of two-to-three cups of green tea a day. When lung cancer was induced, the mice supplemented with green tea showed significantly less tumor growth. The scientists found that green tea suppressed the development of new blood vessels and prevented metastasis. They hypothesize the epigallocatechin gallate is the compound responsible for the suppression of angiogenesis. An article in New Scientist magazine (20 March 2004) mentions that numerous studies suggest that green tea protects against a range of cancers, including lung, prostate and breast cancer. The secret is the antioxidant epigallocatechin gallate (EGCG), according to Hirofumi Tachibana's team at Kyushu University in Japan. Their research showed that growth of human lung cancer cells that have a cell receptor called 67 LR is slowed significantly after drinking just two or three cups of green tea, which contains EGCG. The research also showed that 67 LR is involved in the propagation of prion diseases such as mad cow disease in humans. So knowledge of EGCG's effect on 67 LR might have implications in the treatment of these diseases too.
  • Ovarian cancer Green tea has also shown promise in other areas. For one, it enhances the effectiveness of chemotherapy in ovarian cancer. A study done at the University of Shizuoka, Japan, discovered that oral administration of green tea or theanine, an amino acid found in the leaves of green tea, synergized with the chemotherapy drug Adriamycin in lowering tumor weight. Adriamycin alone was ineffective. Theanine nearly tripled the concentration of adriamycin in the tumor tissue, while decreasing adriamycin levels in healthy tissue. In a more recent study, the same authors showed that theanine also synergizes with Adriamycin to inhibit liver metastases of ovarian cancer. This adds to the growing evidence that natural agents such as green tea can greatly enhance the effectiveness of conventional therapies.
  • Pancreatic cancer Green tea extract in water was shown to inhibit cancer in rodents in such organs as the stomach, duodenum, colon, liver, and pancreas.
  • Prostate cancer In the first known study of the absorption and anti-tumor effects of green and black tea polyphenols in human tissue, researchers at the University of California at Los Angeles were able to detect tea polyphenols in prostate tissue after a very limited consumption of tea. The study was reported at Experimental Biology 2004, in Washington, D.C., as part of the scientific program of the American Society of Nutritional Sciences, one of the six sponsoring scientific societies of this large multi-disciplinary meeting.The scientists found that prostate cancer cells grew more slowly when placed in a medium containing blood serum of men who had consumed either green or black tea for five days compared to serum collected before the men began their tea-drinking regimen. Serum from men who drank comparable amounts of diet or regular soda showed no such slowing in cancer cell proliferation. Research by Curtin University in Perth Western Australia has shown Green tea drinking over a long period of time helps prevent prostate cancer. Professor Colin Binns studied long time drinkers in China. The big sippers who'd been imbibing for 20 years were 2/3 less likely to develop the cancer than the control group.
  • Skin cancer Skin cancer, and the protective effects of catechins on the skin, have been studied extensively. Ultraviolet radiation is known to cause inflammation and immune, making the skin more susceptible to cancer. High doses of epigallocatechin gallate and other catechins are particularly effective in preventing inflammation and skin cancer, especially if delivered in the topical form. Topical epigallocatechin gallate was found to reduce the release of inflammatory prostaglandin's (the E2 series), which play a crucial role in generating free radicals and promoting tumor growth. Due to its antimutagenic and antitumor activities, green tea is a promising candidate for use in topical formulations for skin cancer prevention. Epigallocatechin gallate (EGCG) is a potent polyphenolic antioxidant extracted from green tea. Cima Labs did a study to determine the influence of several factors on the stability of EGCG in solution to obtain information that would facilitate the subsequent development of topical formulations. A second objective was to determine the stability of EGCG in various solvents in the presence and absence of different antioxidants. It was concluded that glycerin-based vehicles are suitable for stabilizing EGCG as a topical formula.
  • Stomach cancer Another type of cancer where high consumption of green tea seems to make a difference is stomach cancer. Men who consumed 7 cups or more of green tea a day had a 31% lower risk of stomach cancer. A Japanese in vitro study found that both green tea extract and epigallocatechin gallate caused a concentration- and time-dependent growth inhibition and apoptosis (programmed cell death) in a line of human stomach cancer cells. A recent animal study done at the Alabama A&M University discovered that phytic acid (found in beans and grains) and green tea synergize to significantly reduce the number of preneoplastic lesions. Again, this points to the general principle that two or more natural agents are more effective together.
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Old 02-08-2011, 11:51 PM
henilvi henilvi is offline
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The benefits of green tea contains the healing process and prevent diseases such as cancer, heart disease, rheumatoid arthritis, multiple infections, immune dysfunction and cardiovascular disease. The benefits of green tea, so that the problem of high cholesterol, improve cholesterol levels in humans.
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Old 03-09-2011, 07:22 PM
herinelvin herinelvin is offline
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Green tea can be acquired in a amount of flavours from humans like Adagio Teas and is aces with honey. Another account of blooming tea is the activity factor. Like coffee, blooming tea has caffeine.
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Old 05-18-2011, 08:05 AM
jakobmartin jakobmartin is offline
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Nice Post. Such a green tea is a best for cancer. It is lots of helps for Fights again cancer. There have been many studies that have shown that green tea catechins are effective at preventing cancer.
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Old 08-06-2011, 12:00 PM
jasperfernandis jasperfernandis is offline
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As we know that the green tea is one of the best natural tea.And its a very best Ant-Oxidant which always fight against the cancer cells and protect your body from the cancers and other infectious diseases too.
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Old 08-17-2011, 08:44 AM
nelsonheell nelsonheell is offline
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Benefits of green tea are:
1. Powerful antioxidant,
2. Can stop development of cancer cells,
3. Can help with treatment for type 1 diabetes,
4. Has been proven to reduce ldl cholesterol,
5. A detoxifier preventing liver disease.
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Old 09-24-2011, 07:20 PM
aldinhomes aldinhomes is offline
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Green tea is one of the best health supplement. It is very useful to reduce the risk of cancer. It is also helpful to control your blood pressure and cholesterol level.
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Old 09-26-2011, 06:43 PM
JacksonWang JacksonWang is offline
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There are some important benefits of Green Tea. I have to say that it is very good health drink and it is very useful to prevent a cancer.

Helps in losing weight
Improve breathing
Reduce heart disease and helps in preventing cancer
Reducing the risk of thrombosis
Increase metabolism and improves immune system
Provide relief from headache.
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Old 09-27-2011, 07:20 AM
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I admit that cancer patients must drink this tea because this is so beneficial for them.
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Old 09-28-2011, 06:14 AM
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Of course green tea is not one of the best, but it's best remedy for breast cancer & fat problem as well. I really appreciate or thanks to that team who find out this as a remedy...!
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Old 09-28-2011, 06:02 PM
monizapunto monizapunto is offline
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These are the benefits of green tea.
It is very important health drink.
It is very helpful to reduce the weight.
It is very useful to reduce the stress.
It Provide relief from headache.
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Old 10-20-2011, 05:50 PM
markscote markscote is offline
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Benefits of green tea are:
Helps in losing weight
Improve breathing
Powerful antioxidant,
Can stop development of cancer cells.
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